Whom portrays Karen Wheeler? Which actor embodies the role of Karen Wheeler in the series? Who is the performer behind Karen Wheeler? Mrs. Wheeler is brought to life by who? What actress acts as the character of Karen Wheeler on the show? Who is the talent bringing Karen Wheeler's character to life? What actor takes on the role of Karen Mrs. Wheeler in the television show? Who takes on the part of Karen Wheeler? Who is the talented individual embodying Karen Wheeler on the series? What actor incarnates the character of Karen Wheeler to the screen?