Whom portrays Mrs. Wheeler mother? Which actress embodies the role of Karen Wheeler in the series? Who is the performer behind Karen Wheeler? Mrs. Wheeler is portrayed by who? Who plays the character of Karen Wheeler on the show? Who is the talent personifying Karen the mother's character to life? Which actress takes on the role of Karen Wheeler in the television show? Whoever acts Karen Wheeler? Who is the talented individual portraying Karen Wheeler on the series? What actor brings the character of Karen Wheeler to the screen?